Santos vs San Lorenzo Prediction, H2H & Stats

Santos vs San Lorenzo: preview and prediction

Santos host San Lorenzo in the World CONMEBOL Sudamericana (Group Stage - 5) on Wednesday, 20th May 2026 at 23:00 at Estadio Urbano Caldeira, Santos.

Santos have been inconsistent, with 2 wins, 2 draws and 1 defeat in their last 5 games (L-W-W-D-D). San Lorenzo have been inconsistent, with 1 win, 3 draws and 1 defeat in their last 5 games (D-D-L-D-W).

Verdict: our pick is Home or Draw at odds of 1.21. We also like Under 2.5, Over 1.5.